This past year (2020), he generated ideas for how exactly to target SARS-CoV-2 linked complications [47]. 1958 in Azerbaijan, from the previous USSR. He graduated from senior high school with Silver Medal in 1976 (Nakhichevan, USSR). In 1982, he graduated summa cum laude in the Azerbaijan Medical Institute in Baku, Azerbaijan, getting an M.D. generally medicine and wellness sciences (Honor Diploma). As a learning student, he was thinking about research function and provided at meetings. He received First Prize at International and USSR Medical Learners Meeting and Congress (1978C1979, Moscow, 1980 Kaunas, Latvian Republic; 1981 Saratov Russia, and 1982 Sank-Petersburg, Russia). In 1989, he received his PhD summa cum laude in Cardiovascular Biology and Pathology in the Ivanovo Medical Institute while performing his research on the Moscow Condition University as well as the Russian Cardiology Analysis Center. Third ,, Gjumrakch received postdoctoral schooling under the esteemed British Heart Base Grant Plan in the School University London (consultant Teacher Geoffrey Burnstock), focusing on medicine. Teacher Aliev possessed an encyclopedic understanding in an array of technological fields; however, his main research concentrate was from the advancement of unique treatment and technology protocols for age-associated illnesses. He was known for his function in the areas of gerontology [1 internationally,2,3,4,5], [6 oncology,7,8,9,10,11,12,13,14,15], cardiovascular illnesses [16,17,18,19], endocrinology [2,20,21], and neurodegenerative illnesses [15,20,22,23,24,25,26,27,28,29,30,31,32]. His analysis publications in the function of vascular and mitochondrial elements in the pathogenesis of maturing [2,3,5], atherosclerosis [33,34], ischemia-reperfusion [18,35,36,37], heart stroke [4,18,35,38], and Alzheimers disease (Advertisement) [23,24,33,39,40,41,42,43] tend to Metaproterenol Sulfate be cited (Desk 1). Additionally, Teacher Aliev and his co-workers were the first ever to propose the function from the energy turmoil as a generating power for the acceleration of maturing [6,35,44]. He authored and co-authored a lot more than 400 peer-reviewed journal content and reserve chapters (https://www.researchgate.net/profile/Gjumrakch_Aliev/research (accessed on 20 Feb 2021)), aswell as more than 170 scientific abstracts of meeting presentations on neurodegenerative disease analysis, cardio- and cerebrovascular illnesses, cancers, and electron microscopy. He previously many patents and rationalizations also. To his passing Prior, Teacher Aliev was the Task Business lead and Movie director Investigator of many international scientific tasks. Table 1 Top 10 Prof. Alievs cited content in neuro-scientific Alzheimers disease and neuroinflammation highly. Source of details; https://scholar.google.com/citations?consumer=a_TYBosAAAAJ&hl=en (accessed in 20 March 2021). thead th align=”middle” valign=”middle” design=”border-top:solid slim;border-bottom:solid slim” rowspan=”1″ colspan=”1″ Name, Reference /th th align=”middle” valign=”middle” design=”border-top:solid slim;border-bottom:solid slim” rowspan=”1″ colspan=”1″ # of that time period Cited in 20 March 2021 /th th align=”middle” valign=”middle” design=”border-top:solid slim;border-bottom:solid slim” rowspan=”1″ colspan=”1″ Year of Publication /th /thead Oxidative damage may be the first event in Alzheimer disease [22]19612001Mitochondrial abnormalities in Alzheimers disease [39]1375Activation and redistribution of c-jun N-terminal kinase/stress turned on protein kinase in degenerating neurons in Alzheimers disease [45]449Role of mitochondrial dysfunction in Alzheimers disease [23]3792002Is oxidative damage the essential pathogenic mechanism of Alzheimers and various other neurodegenerative diseases? [24]358The function of oxidative tension in the pathophysiology of cerebrovascular lesions in Alzheimers disease [44]205Microtubule decrease in Alzheimers disease and maturing is indie of filament development [66]3272003Vascular oxidative tension in Alzheimer disease [67]2092007Nucleic acidity oxidation in Alzheimer disease [41]2102008Oxidative tension mediated mitochondrial and vascular lesions as markers in the pathogenesis of Alzheimer disease [33]1482014 Suggestions for the utilization and interpretation of assays for monitoring autophagy [68]94552021 Open up in another window The thought of medication optimization in the treating several pathological circumstances associated with maturing and irritation was the primary aim of a lot of Prof. Alievs studies. Elderly patients in every countries are recommended a small number of medications that frequently initiate unwanted effects and provoke additional prescription of extra products. Polypharmacy, a habit and/or a necessity to take too.His recent projects were supported by the Russian Academy of Sciences (RSCF No. and the committee on Science, Technology and Innovation (STI) for UNESCAP. Open in a separate window Figure 1 Professor Aliev in his Laboratory, Sechenov University, Moscow (2019). Professor Aliev was born on 1 September 1958 in Azerbaijan, of the former USSR. He graduated from high school with Gold Medal in 1976 (Nakhichevan, USSR). In 1982, he graduated summa cum laude from the Azerbaijan Medical Institute in Baku, Azerbaijan, receiving an M.D. in general medicine and health sciences (Honor Diploma). As a student, he was interested in research work and presented at conferences. He received First Award at International and USSR Medical Students Conference and Congress (1978C1979, Moscow, 1980 Kaunas, Latvian Republic; 1981 Saratov Russia, and 1982 Sank-Petersburg, Russia). In 1989, he received his PhD summa cum laude in Cardiovascular Biology and Pathology from the Ivanovo Medical Institute while conducting his research at the Moscow State University and the Russian Cardiology Research Center. Following this, Gjumrakch received postdoctoral training under the prestigious British Heart Foundation Grant Program in the University College London (advisor Professor Geoffrey Burnstock), specializing in medicine. Professor Aliev possessed an encyclopedic knowledge in a wide range of scientific fields; however, his main research focus was linked to the development of unique technologies and treatment protocols for age-associated diseases. He was recognized internationally for his work in the fields of gerontology [1,2,3,4,5], oncology [6,7,8,9,10,11,12,13,14,15], cardiovascular diseases [16,17,18,19], endocrinology [2,20,21], and neurodegenerative diseases [15,20,22,23,24,25,26,27,28,29,30,31,32]. His research publications on the role of vascular and mitochondrial factors in the pathogenesis of aging [2,3,5], atherosclerosis [33,34], ischemia-reperfusion [18,35,36,37], stroke [4,18,35,38], and Alzheimers disease (AD) [23,24,33,39,40,41,42,43] are often cited (Table 1). Additionally, Professor Aliev and his colleagues were the first to propose the role of the energy crisis as a driving force for the acceleration of aging [6,35,44]. He authored and co-authored more than 400 peer-reviewed journal articles and Metaproterenol Sulfate book chapters (https://www.researchgate.net/profile/Gjumrakch_Aliev/research (accessed on 20 February 2021)), as well as over 170 scientific abstracts of conference presentations on neurodegenerative disease research, cardio- and cerebrovascular diseases, cancer, and electron microscopy. He also had several patents and rationalizations. Prior to his passing, Professor Aliev was the Project Director and Lead Investigator of several international scientific projects. Table 1 Top 10 10 Prof. Alievs Metaproterenol Sulfate highly cited articles in the field of Alzheimers disease and neuroinflammation. Source of information; https://scholar.google.com/citations?user=a_TYBosAAAAJ&hl=en (accessed on 20 March 2021). thead th align=”center” valign=”middle” style=”border-top:solid thin;border-bottom:solid thin” rowspan=”1″ colspan=”1″ Title, Reference /th th align=”center” valign=”middle” style=”border-top:solid thin;border-bottom:solid thin” rowspan=”1″ colspan=”1″ # of Times Cited on 20 March 2021 /th th align=”center” valign=”middle” style=”border-top:solid thin;border-bottom:solid thin” rowspan=”1″ colspan=”1″ Year of Publication /th /thead Oxidative damage is the earliest event in Alzheimer disease [22]19612001Mitochondrial abnormalities in Alzheimers disease [39]1375Activation and redistribution of c-jun N-terminal kinase/stress activated protein kinase in degenerating neurons in Alzheimers disease [45]449Role of mitochondrial dysfunction in Alzheimers disease [23]3792002Is oxidative damage the fundamental pathogenic mechanism of Alzheimers and other neurodegenerative diseases? [24]358The role of oxidative stress in the pathophysiology of cerebrovascular lesions in Alzheimers disease [44]205Microtubule reduction in Alzheimers disease and aging is independent of filament formation [66]3272003Vascular oxidative stress in Alzheimer disease [67]2092007Nucleic acid oxidation in Alzheimer disease [41]2102008Oxidative stress mediated mitochondrial and vascular lesions as markers in the pathogenesis of Alzheimer disease [33]1482014 Guidelines for the use and interpretation of assays for monitoring autophagy [68]94552021 Open in a separate window The idea of drug optimization in the treatment of several pathological conditions associated with aging and inflammation was the core aim of.He supported my passion for the study of foreign languages which has, in turn, allowed me to become a professional in my job today. and Innovation (STI) for UNESCAP. Open in a separate window Figure 1 Professor Aliev in his Laboratory, Sechenov University, Moscow (2019). Professor Aliev was born on 1 September 1958 in Azerbaijan, of the former USSR. He graduated from high school with Gold Medal in 1976 (Nakhichevan, USSR). In 1982, he graduated summa cum laude from the Azerbaijan Medical Institute in Baku, Azerbaijan, receiving an M.D. in general medicine and health sciences (Honor Diploma). As a student, he was interested in research work and presented at conferences. He received First Award at International and USSR Medical Students Conference and Congress (1978C1979, Moscow, 1980 Kaunas, Latvian Republic; 1981 Saratov Russia, and 1982 Sank-Petersburg, Russia). In Rabbit Polyclonal to eIF4B (phospho-Ser422) 1989, he received his PhD summa cum laude in Cardiovascular Biology and Pathology from the Ivanovo Medical Institute while conducting his research at the Moscow State University and the Russian Cardiology Research Center. Following this, Gjumrakch received postdoctoral training under the prestigious British Heart Foundation Grant Program in the University College London (advisor Professor Geoffrey Burnstock), specializing in medicine. Professor Aliev possessed an encyclopedic knowledge in a wide range of scientific fields; however, his main research focus was linked to the development of unique technologies and treatment protocols for age-associated diseases. He was recognized internationally for his work in the fields of gerontology [1,2,3,4,5], oncology [6,7,8,9,10,11,12,13,14,15], cardiovascular diseases [16,17,18,19], endocrinology [2,20,21], and neurodegenerative diseases [15,20,22,23,24,25,26,27,28,29,30,31,32]. His research publications on the role of vascular and mitochondrial factors in the pathogenesis of aging [2,3,5], atherosclerosis [33,34], ischemia-reperfusion [18,35,36,37], stroke [4,18,35,38], and Alzheimers disease Metaproterenol Sulfate (AD) [23,24,33,39,40,41,42,43] are often cited (Table 1). Additionally, Professor Aliev and his colleagues were the first to propose the role of the energy crisis as a driving force for the acceleration of maturing [6,35,44]. He authored and co-authored a lot more than 400 peer-reviewed journal content and reserve chapters (https://www.researchgate.net/profile/Gjumrakch_Aliev/research (accessed on 20 Feb 2021)), aswell as more than 170 scientific abstracts of meeting presentations on neurodegenerative disease analysis, cardio- and cerebrovascular illnesses, cancer tumor, and electron microscopy. He also acquired many patents and rationalizations. Ahead of his passing, Teacher Aliev was the Task Movie director and Lead Investigator of many international technological projects. Desk 1 Top 10 Prof. Alievs extremely cited content in neuro-scientific Alzheimers disease and neuroinflammation. Way to obtain details; https://scholar.google.com/citations?consumer=a_TYBosAAAAJ&hl=en (accessed in 20 March 2021). thead th align=”middle” valign=”middle” design=”border-top:solid slim;border-bottom:solid slim” rowspan=”1″ colspan=”1″ Name, Reference /th th align=”middle” valign=”middle” design=”border-top:solid slim;border-bottom:solid slim” rowspan=”1″ colspan=”1″ # of that time period Cited in 20 March 2021 /th th align=”middle” valign=”middle” design=”border-top:solid slim;border-bottom:solid slim” rowspan=”1″ colspan=”1″ Year of Publication /th /thead Oxidative damage may be the first event in Alzheimer disease [22]19612001Mitochondrial abnormalities in Alzheimers disease [39]1375Activation and redistribution of c-jun N-terminal kinase/stress turned on protein kinase in degenerating neurons in Alzheimers disease [45]449Role of mitochondrial dysfunction in Alzheimers disease [23]3792002Is oxidative damage the essential pathogenic mechanism of Metaproterenol Sulfate Alzheimers and various other neurodegenerative diseases? [24]358The function of oxidative tension in the pathophysiology of cerebrovascular lesions in Alzheimers disease [44]205Microtubule decrease in Alzheimers disease and maturing is unbiased of filament development [66]3272003Vascular oxidative tension in Alzheimer disease [67]2092007Nucleic acidity oxidation in Alzheimer disease [41]2102008Oxidative tension mediated mitochondrial and vascular lesions as markers in the pathogenesis of Alzheimer disease [33]1482014 Suggestions for the utilization and interpretation of assays for monitoring autophagy [68]94552021 Open up in another window The thought of medication optimization in the treating several pathological circumstances associated with maturing and irritation was the primary aim of a lot of Prof. Alievs studies. Elderly patients in every countries are recommended a small number of medications that frequently initiate unwanted effects and provoke additional prescription of extra products. Polypharmacy, a habit and/or essential to take way too many medications, is normally along with a financial health insurance and burden dangers. Taking into consideration the benefit of much less proven-to-be-beneficial and harmful chemical compounds, Prof. Alievs function strongly supports the introduction of oxidative stress-targeting and multi-purpose therapies as a procedure for treat age-associated pathologies. Teacher Aliev had excellent expertise in a variety of areas of microscopic evaluation. Having acquired a long time of knowledge in teaching and analysis with light microscopy, electron microscopy (EM), 2-photon microscopy, atomic drive, and confocal microscopy, he created pioneering work in various regions of EM-based methods. These methods included cytological in situ hybridization on the light and electron microscopic amounts using non-isotopic colloidal precious metal probes [35,44], peroxidase-anti-peroxidase [44,45,46], and pre- and post-embedding one, double, and triple immunogold quantification and cytochemistry [37,39]..