Our results show that upon TLR4 activation, TUT7, but not TUT4, is upregulated and TUT7 subsequently associates with and oligouridylates to regulate cytokine production. Here we reveal that TLR4 activation induces TUT7, which in turn selectively regulates the production of a subset of cytokines, including Interleukin 6 (IL-6). TUT7 regulates IL-6 expression by controlling ribonuclease…
Category: mGlu8 Receptors
The irradiated Jurkat cells were added to 50,000 BALF cells (plated the same as those explained for phagocytosis to remove all other cell types, thus macrophages remain) with macrophage incomplete media and incubated at 37C for 2 hr
The irradiated Jurkat cells were added to 50,000 BALF cells (plated the same as those explained for phagocytosis to remove all other cell types, thus macrophages remain) with macrophage incomplete media and incubated at 37C for 2 hr. Pathway Analysis. C) These are the pathways recognized in genes that were RX-3117 decreased in the BALBmice…